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Males tend to get more severe acne than females. Acne develops in the oil-producing structures of the skin called sebaceous glands, which vary considerably in structure and size. One or more sebaceous glands accompany each hair follicle. These glands secrete an oily mixture called sebum which normally passes through the hair follicle to the skin surface. During adolescence, the sebaceous glands grow larger and produce more sebum, especially in the face, chest and back areas. Acne occurs when the normal route of sebum to the skin surface is blocked. In the case of severe acne, the sebum builds up in the gland and mixes with dead cells. This accumulation finally ruptures the follicle wall, forming an inflamed nodule under the skin. Scarring usually results from these nodules, which is why treatment is important, the earlier, the better. 
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